Acyclovir is acyclic purine nucleoside analogue active against herpes
simplex virus, varicella zoster, Epstein-Barr virus and
cytomegalovirus. In the cell, undergo phosphorylation acyclovir
acyclovir triphosphate into an active form that inhibit the herpes
simplex virus DNA polymerase and viral DNA replication, thereby
preventing viral DNA synthesis without affecting normal cell processes.
Acyclovir Pharmacology
Acyclovir
is an antiviral agent highly active in vitro against herpes simplex
virus (HSV) types I and II, and varicella zoster virus. Upon entry into
the infected cell, the phosphorylated form of the active compound
Acyclovir Acyclovir trifosfate. The initial phase of the process depends
on the enzyme thymidine kinase viral-coded. Acyclovir trifosfate act as
inhibitors and as a false substrate for the herpes-specified DNA
polymerase which prevents viral DNA synthesis without affecting normal
cellular processes.
Treatment of herpes simplex virus
infections of the skin and mucous membranes including initial and
recurrent genital herpes / recurrent, herpes zoster (shingles / shingles
/ shingles). Preventing recurrence of herpes simplex infections in
patients with strong immune systems. Preventing herpes simplex infection
in patients with poor immune systems.
Another
acyclovir pharmacology is a treatment of herpes simplex virus infections
of the skin and mucous membranes including initial and recurrent
genital herpes / recurrent, herpes zoster (shingles / shingles /
shingles); preventing recurrence of herpes simplex infections in
patients with strong immune systems; preventing herpes simplex infection
in patients with poor immune systems.
Acyclovir Indication
Acyclovir
indication such as treatment of herpes simplex virus on the skin and
mucus membranes, including initial and recurrent genital herpes;
treatment of herpes zoster and varicella infections; treatment of
infections caused by the herpes simplex of the skin and mucous membranes
including initial and recurrent genital herpes, herpes simplex
infection prevention in immuno-compromised patients; treatment of herpes
zoster infection.